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How to get fromKnoxville to Poplar Bluffby plane, car, bus, or train

Find Transport to Poplar Bluff

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There are 7 ways to get from Knoxville to Poplar Bluff by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Mc Kellar-Sipes Regional Airport, drive

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Mc Kellar-Sipes Regional Airport (MKL)plane plane TYS - MKL
    2. Drive from Mc Kellar-Sipes Regional Airport (MKL) to Poplar Bluffcar car
    6h 23m
    $181–657

  2. Drive  415.8 mi

    cheapest
    1. Drive from Knoxville to Poplar Bluffcar car 415.8 mi
    7h 9m
    $76–110

  3. Bus, drive

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    4. Drive from Flying J - Matthews to Poplar Bluffcar car
    12h 57m
    $193–285

  4. Fly Mcghee Tyson Airport to Jonesboro Municipal Airport, drive

    1. Fly from Mcghee Tyson Airport (TYS) to Jonesboro Municipal Airport (JBR)plane plane TYS - JBR
    2. Drive from Jonesboro Municipal Airport (JBR) to Poplar Bluffcar car
    6h 2m
    $231–788

  5. Bus to Nashville, fly to Jonesboro Municipal Airport, drive

    1. Take the bus from Knoxville to Nashvillebus bus
    2. Fly from Nashville (BNA) to Jonesboro Municipal Airport (JBR)plane plane BNA - JBR
    3. Drive from Jonesboro Municipal Airport (JBR) to Poplar Bluffcar car
    9h 16m
    $277–690

  6. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Poplar Bluff Stationtrain train
    16h 21m
    $268–394

  7. Bus, train via Carbondale

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    4. Take the train from St. Louis to Poplar Bluff Stationtrain train
    16h 36m
    $267–381

Mcghee Tyson Airport (TYS) to Mc Kellar-Sipes Regional Airport (MKL) flights

Calendar29Weekly Planes
Duration5h 11mAverage Duration
Ticket$107Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Poplar Bluff.ExpandLaunch map view
  • Distance: 424.9 mi
  • Duration: 6h 23m

What companies run services between Knoxville, TN, USA and Poplar Bluff, MO, USA?

There is no direct connection from Knoxville to Poplar Bluff. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Mc Kellar-Sipes Regional Airport (MKL), then drive to Poplar Bluff. Alternatively, you can take a vehicle from Knoxville to Poplar Bluff via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, and Flying J - Matthews in around 12h 57m.

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