There are 5 ways to get from Florence to Tampa by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Florence Regional Airport
best- Fly from Florence Regional Airport (FLO) to Tampa (TPA)plane FLO - TPA
5h 43m$87–444Bus
- Take the bus from Florence to Orlando Bus Stationbus FlixBus N2472
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus FlixBus N2411 / ...
11h 6m$92–150Train (Amtrak)
- Take the train from Florence Station to Kissimmee Amtrak Stationtrain Silver Meteor
- Take the train from Kissimmee Amtrak Station to Tampatrain Floridian
13h 4m$321–496Drive 497 mi
- Drive from Florence to Tampacar 497 mi
8h 30m$91–131Bus to Myrtle Beach, fly
- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to Tampa (TPA)plane MYR - TPA
5h 34m$114–373
Florence to Tampa by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Florence to Tampa is to drive which costs $90 - $140 and takes 8h 30m.
The fastest way to get from Florence to Tampa is to bus and fly which takes 5h 34m and costs $110 - $380.
No, there is no direct bus from Florence to Tampa station. However, there are services departing from Florence and arriving at Tampa Bus Station via Orlando Bus Station. The journey, including transfers, takes approximately 11h 6m.
No, there is no direct train from Florence station to Tampa. However, there are services departing from Florence Station and arriving at Tampa via Kissimmee Amtrak Station. The journey, including transfers, takes approximately 13h 4m.
The distance between Florence and Tampa is 473 miles. The road distance is 499.9 miles.
The best way to get from Florence to Tampa without a car is to bus which takes 11h 6m and costs $90 - $150.
It takes approximately 5h 43m to get from Florence to Tampa, including transfers.
Florence to Tampa bus services, operated by Flixbus USA, depart from Florence station.
Florence to Tampa train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Tampa is to fly which takes 5h 43m and costs $85 - $450. Alternatively, you can bus, which costs $90 - $150 and takes 11h 6m, you could also train, which costs $320 - $500 and takes 13h 4m.
What companies run services between Florence, SC, USA and Tampa, FL, USA?
American Airlines flies from Florence Regional Airport (FLO) to Tampa (TPA) twice daily. Alternatively, you can take a vehicle from Florence to Tampa Bus Station via Florence and Orlando Bus Station in around 11h 6m.
- Website
- aa.com
Flights from Florence Regional Airport to Tampa via Charlotte
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $75–430
Flights from Myrtle Beach to Tampa via Charlotte
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $75–440
- Website
- flybreeze.com
Flights from Myrtle Beach to Tampa
- Ave. Duration
- 1h 39m
- When
- Wednesday, Saturday, Monday, Friday, Thursday, and Sunday
- Estimated price
- $90–340
Flights from Myrtle Beach to Tampa via Fort Lauderdale
- Ave. Duration
- 3h 57m
- When
- Monday and Friday
- Estimated price
- $90–340
- Website
- delta.com
Flights from Myrtle Beach to Tampa via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $80–450
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Kissimmee Amtrak Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $280–440
- Website
- Amtrak
Train from Kissimmee Amtrak Station to Tampa
- Ave. Duration
- 1h 44m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Florence to Orlando Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a week
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $12–19
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $13–22
- Website
- Greyhound
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $11–18
- Website
- Greyhound
Want to know more about travelling around United States
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Florence to Tampa bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Florence to Tampa train services, operated by Amtrak, arrive at Kissimmee Amtrak Station.
Yes, the driving distance between Florence to Tampa is 500 miles. It takes approximately 8h 30m to drive from Florence to Tampa.
Book your Florence to Tampa train tickets online with Omio.
Book your Florence to Tampa bus tickets online with Omio.
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