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How to get fromFort Myers to Lafayetteby taxi, plane, shuttle, bus (Flixbus, Greyhound, Amtrak), bus, train, or car

Find Transport to Lafayette

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There are 7 ways to get from Fort Myers to Lafayette by taxi, plane, shuttle, bus (Flixbus, Greyhound, Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Punta Gorda Airport, fly, shuttle

    best
    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Indianapolis (IND)plane plane PGD - IND
    3. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    4h 44m
    $207–772

  2. Bus to Tampa, fly, shuttle

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Indianapolis (IND)plane plane TPA - IND
    3. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    9h 27m
    $147–669

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Lafayette Amtrak Stationbus bus
    28h 50m
    $210–336

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Chicago Union Stationtrain train
    3. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus
    2d
    $998–1,680

  5. Drive  1,104.6 mi

    1. Drive from Fort Myers to Lafayettecar car 1,104.6 mi
    20h 13m
    $202–292

  6. Fly from Ft. Myers, shuttle

    1. Fly from Ft. Myers (RSW) to Indianapolis (IND)plane plane RSW - IND
    2. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    7h 7m
    $158–790

  7. Bus to Sarasota–Bradenton International Airport, fly, shuttle

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Indianapolis (IND)plane plane SRQ - IND
    3. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    7h 49m
    $207–1,055

Fort Myers to Lafayette by bus

Calendar5Weekly Buses
Duration28h 50mAverage Duration
Ticket$210Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Fort Myers to Lafayette.ExpandLaunch map view
  • Distance: 1,012.3 mi
  • Duration: 4h 44m

What companies run services between Fort Myers, FL, USA and Lafayette, IN, USA?

You can take a bus from Fort Myers Bus Stop to Lafayette Amtrak Station via Tampa Bus Station, Atlanta Bus Station, and Indianapolis Union Station in around 28h 50m.

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