There are 4 ways to get from Ecuador to Panama by plane, bus, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from José Joaquín De Olmedo International Airport
best- Fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY)plane GYE - PTY
3h 10m$265–538Bus, ferry, drive via Ipiales
- Take the bus from Guayaquil to Terminal Terrestre Quitumbebus
- Take the bus from Terminal Terrestre Quitumbe to Rumichacabus
- Take the bus from Terminales de Transportes de Ipiales to Terminal Salitrebus
- Take the bus from Terminal Salitre to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
8d 14h$872–958Car to Mariscal Sucre International Airport, fly
- Drive from Quito to Quito Airportcar
- Fly from Mariscal Sucre International Airport (UIO) to Tocumen International Airport (PTY)plane UIO - PTY
5h 1m$355–665Bus, ferry, drive
- Take the bus from Terminal Terrestre de Guayaquil to Cúcutabus
- Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
8d 17h$899–1,043
José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) flights
Comparing Your Travel Options
The cheapest way to get from Ecuador to Panama is to car and fly which costs $350 - $700 and takes 5h 1m.
The fastest way to get from Ecuador to Panama is to fly which takes 3h 10m and costs $260 - $550.
The distance between Ecuador and Panama is 1284 km.
It takes approximately 3h 10m to get from Ecuador to Panama, including transfers.
There are 893+ hotels available in Panama.
What companies run services between Ecuador and Panama?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) every 4 hours.
- Website
- copaair.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $65–370
Flights from Mariscal Sucre International Airport to Tocumen International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $60–340
- Website
- klm.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $65–370
Flights from Mariscal Sucre International Airport to Tocumen International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $60–340
Flights from Mariscal Sucre International Airport to Tocumen International Airport via José Joaquín De Olmedo International Airport
- Ave. Duration
- 4h 35m
- When
- Tuesday to Sunday
- Estimated price
- $75–400
- Website
- avianca.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 5h 7m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $210–480
Flights from Mariscal Sucre International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $290–650
- Phone
- +593 98 875 2804
- coop.transporte.aerotaxi@gmail.com
- Website
- Cooperativa de Transportes Aerotaxi
Bus from Guayaquil to Terminal Terrestre Quitumbe
- Ave. Duration
- 9h
- Frequency
- Every 4 hours
- Estimated price
- $11–12
- Website
- Cooperativa de Transportes Aerotaxi
- Website
- Cooperativa de Transportes Aerotaxi
Bus from Guayaquil to Terminal Terrestre Quitumbe
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- $15–22
- Schedules at
- Trans Esmeraldas S.A.
Bus from Terminal Terrestre Quitumbe to Rumichaca
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $30–40
- Website
- Lineas De Los Andes
Bus from Terminal Terrestre de Guayaquil to Cúcuta
- Ave. Duration
- 44h
- Frequency
- Once daily
- Estimated price
- $130–240
- Website
- Lineas De Los Andes
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $58
- Schedules at
- continentalbus.com.co
- Phone
- +57 601 4249090
- contactenos@bolivariano.com.co
- Website
- bolivariano.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $55–80
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +57 323 563 9139
- servicioalcliente@copetran.com
- Website
- copetran.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 23h
- Frequency
- Every 3 hours
- Estimated price
- $60–85
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $60–85
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- $45–65
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $45–65
- Phone
- +57 310 7883333
- gerencia@cootransbol.com
- Website
- concordeoficial.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $65–95
- Schedules at
- concordeoficial.com
- Book at
- concordeoficial.com
- Phone
- 01 800 051 8001
- contactenos@expresobrasilia.com
- Website
- expresobrasilia.com
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 2m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- $40–60
- Phone
- +57 310 704 0425
- bluesailinginfo@gmail.com
- Website
- Blue Sailing
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
- Phone
- +593 98 414 6312
- fantasytravelecuador@gmail.com
- Website
- Fantasy Travel Ecuador
Car from Quito to Quito Airport
- Ave. Duration
- 20 min
- Frequency
- On demand
- Estimated price
- $25
- Schedules at
- Fantasy Travel Ecuador
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Travelling around the UAE, Bali: What to do if Mount Agung erupts, and 5 delightfully under-the-radar French towns you need to visit - to help you get the most out of your next trip.