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How to get fromEast Peoria to Mayo Clinicby plane, bus, train, or car

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There are 7 ways to get from East Peoria to Mayo Clinic by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Peoria International Airport to Rochester

    best
    1. Fly from Peoria International Airport (PIA) to Rochester (RST)plane plane PIA - RST
    7h 30m
    $53–382

  2. Bus, train via Milwaukee

    1. Take the bus from Peoria Amtrak Station to Galesburg Amtrak Stationbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    15h 22m

  3. Bus, train

    1. Take the bus from Peoria Amtrak Station to Galesburg Amtrak Stationbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    17h 9m

  4. Drive  330.6 mi

    1. Drive from East Peoria to Mayo Cliniccar car 330.6 mi
    6h 30m
    $61–88

  5. Drive to The Eastern Iowa Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from East Peoria to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Minneapolis–Saint Paul International Airport (MSP)plane plane CID - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 26m
    $132–466

  6. Bus to Chicago O'Hare International Airport, fly to Rochester

    1. Take the bus from Peoria to O'Hare International Terminal 2bus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    9h 40m
    $87–371

  7. Bus

    1. Take the bus from Peoria to O'Hare International Terminal 2bus bus
    2. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    15h 30m
    $122–194

Peoria International Airport (PIA) to Rochester (RST) flights

Calendar49Weekly Planes
Duration6h 19mAverage Duration
Ticket$54Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from East Peoria to Mayo Clinic.ExpandLaunch map view
  • Distance: 284.5 mi
  • Duration: 7h 30m

What companies run services between East Peoria, IL, USA and Mayo Clinic, MN, USA?

American Airlines and United Airlines fly from Peoria International Airport (PIA) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from 100 Washington to Mayo Clinic via Peoria, O'Hare International Terminal 2, O'Hare, Rosemont, Rosemont CTA Station - Bus Stop F, Multi-Modal/Rental Car Facility, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 15h 30m.

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