There are 10 ways to get from Durham to Indiana by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Raleigh-Durham International Airport, fly to Indianapolis
best- Take the bus from Durham Station to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane RDU - IND
5h 22m$166–378Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport, train
cheapest- Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane RDU - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 36m$69–350Bus
- Take the bus from Durham to Greensboro Bus Stopbus
- Take the bus from Greensboro to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Indianapolis Union Stationbus
18h$84–162Train (Amtrak)
- Take the train from Durham Amtrak Station to Greensborotrain
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
21h 49m$455–746Drive 587.9 mi
- Drive from Durham to Indianapoliscar 587.9 mi
10h 27m$108–155Fly Raleigh-Durham International Airport to Chicago Midway International Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane RDU - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 1m$164–240Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport, train
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane GSO - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 25m$130–471Train to Charlotte Douglas International Airport, fly to Indianapolis
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane CLT - IND
7h 27m$174–682Bus via Atlanta (Flixbus)
- Take the bus from Durham to Atlanta Downtownbus FlixBus N2470
- Take the bus from Atlanta Bus Station to Indianapolisbus FlixBus 2512
19h 19m$140–218Train via Arlington (Amtrak)
- Take the train from Durham Amtrak Station to Alexandriatrain Carolinian
- Take the train from Alexandria to Indianapolistrain Cardinal
25h 29m$569–924
Durham to Indiana by bus
Comparing Your Travel Options
The cheapest way to get from Durham to Indiana is to bus which costs $80 - $170 and takes 18h.
The fastest way to get from Durham to Indiana is to bus and fly which takes 5h 22m and costs $160 - $380.
No, there is no direct bus from Durham to Indiana station. However, there are services departing from Durham and arriving at Indianapolis Union Station via Greensboro, Winston Salem and Columbus. The journey, including transfers, takes approximately 18h.
No, there is no direct train from Durham station to Indiana. However, there are services departing from Durham Amtrak Station and arriving at Indianapolis via Greensboro and Charlottesville. The journey, including transfers, takes approximately 21h 49m.
The distance between Durham and Indiana is 523 miles. The road distance is 591.4 miles.
The best way to get from Durham to Indiana without a car is to bus which takes 18h and costs $80 - $170.
It takes approximately 5h 22m to get from Durham to Indiana, including transfers.
Durham to Indiana bus services, operated by Flixbus USA, depart from Durham station.
Durham to Indiana train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to Indiana is to bus which takes 18h and costs $80 - $170. Alternatively, you can train, which costs $450 - $750 and takes 21h 49m.
What companies run services between Durham, NC, USA and Indiana, USA?
You can take a bus from Durham to Indianapolis Union Station via Greensboro, Winston Salem, and Columbus in around 18h. Alternatively, you can take a train from Durham Amtrak Station to Indianapolis via Greensboro and Charlottesville in around 21h 49m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Indianapolis via Charlotte Douglas International Airport
- Ave. Duration
- 3h 58m
- When
- Tuesday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 32m
- When
- Every day
- Estimated price
- $55–330
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport via Pittsburgh
- Ave. Duration
- 5h 34m
- When
- Tuesday and Wednesday
- Estimated price
- $60–340
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $60–370
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $65–380
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Reagan Washington
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–420
Flights from Charlotte Douglas International Airport to Indianapolis
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $85–550
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Indianapolis via Nashville
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Indianapolis via Baltimore
- Ave. Duration
- 3h 51m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 1m
- When
- Sunday and Saturday
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $70–410
Flights from Charlotte Douglas International Airport to Indianapolis via Nashville
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $95–600
Flights from Charlotte Douglas International Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–650
Flights from Charlotte Douglas International Airport to Indianapolis via Baltimore
- Ave. Duration
- 4h 15m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $120–650
- Website
- united.com
Flights from Raleigh-Durham International Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- $55–330
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $60–370
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $75–410
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Indianapolis
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $90–550
Flights from Raleigh-Durham International Airport to Indianapolis via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–430
Flights from Raleigh-Durham International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $60–340
Flights from Piedmont Triad International Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $80–430
Flights from Charlotte Douglas International Airport to Indianapolis via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $100–600
Flights from Charlotte Douglas International Airport to Indianapolis via Detroit
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Amtrak
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $80–130
- Website
- Amtrak
Train from Durham Amtrak Station to Alexandria
- Ave. Duration
- 6h 33m
- Frequency
- Once daily
- Estimated price
- $170–280
- Website
- Amtrak
Train from Alexandria to Indianapolis
- Ave. Duration
- 17h 56m
- Frequency
- 3 times a week
- Estimated price
- $390–650
- Website
- Amtrak
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Schedules at
- godurhamtransit.org
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- $8–14
- Website
- Greyhound
Bus from Columbus to Indianapolis Union Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- $7–12
- Schedules at
- Flixbus USA
Bus from Durham to Atlanta Downtown
- Ave. Duration
- 6h 30m
- Frequency
- 4 times a week
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Indianapolis
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
- Phone
- +1 704-348-1200
- info@sunwaycharters.com
- Website
- Sunway Charters
Bus from Greensboro to Winston-Salem
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $6–9
- Schedules at
- Sunway Charters
- Passenger
- $6–9
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
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Durham to Indiana bus services, operated by Flixbus USA, arrive at Atlanta Downtown station.
Durham to Indiana train services, operated by Amtrak, arrive at Greensboro station.
Yes, the driving distance between Durham to Indiana is 591 miles. It takes approximately 10h 27m to drive from Durham to Indiana.
Book your Durham to Indiana train tickets online with Omio.
Book your Durham to Indiana bus tickets online with Omio and FlixBus.
There are 871+ hotels available in Indiana.