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How to get fromDurham to Greenvilleby train, bus, car, plane, bus (Greyhound, Flixbus), or taxi

Find Transport to Greenville

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There are 7 ways to get from Durham to Greenville by train, bus, car, plane, bus (Greyhound, Flixbus), or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train Piedmont / ...
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    6h 41m
    $120–192

  2. Drive  238.5 mi

    cheapest
    1. Drive from Durham to Greenvillecar car 238.5 mi
    4h 9m
    $44–63

  3. Fly Raleigh-Durham International Airport to Greenville–Spartanburg International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP)plane plane RDU - GSP
    5h 27m
    $109–540

  4. Bus

    1. Take the bus from Durham to Charlotte Bus Stationbus bus Greyhound US0670
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    6h 52m
    $62–107

  5. Bus via Charlotte

    1. Take the bus from Durham, NC - 3446 Hillsborough Rd to Charlotte, NC - 3302 Queen City Drbus bus New York
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    9h 29m
    $54–111

  6. Train to Charlotte Douglas International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Greenville–Spartanburg International Airport (GSP)plane plane CLT - GSP
    5h 48m
    $177–616

  7. Train to Charlotte Douglas International Airport, fly to Asheville Regional Airport, taxi

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL)plane plane CLT - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 39m
    $262–601

Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) flights

Calendar103Weekly Planes
Duration4h 1mAverage Duration
Ticket$70Cheapest Price
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Comparing Your Travel Options

Map of how to get from Durham to Greenville.ExpandLaunch map view
  • Distance: 263.4 mi
  • Duration: 6h 41m

What companies run services between Durham, NC, USA and Greenville, SC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Durham to Greenville via Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 6h 52m.

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