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How to get fromDetroit to Tupeloby plane, car, bus (Greyhound, Flixbus), train, bus, bus (Flixbus, Greyhound), or bus (Greyhound)

Find Transport to Tupelo

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There are 11 ways to get from Detroit to Tupelo by plane, car, bus (Greyhound, Flixbus), train, bus, bus (Flixbus, Greyhound), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Detroit (DTW) to Golden Triangle Regional Airport (GTR)plane plane DTW - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    7h 12m
    $113–619

  2. Bus

    1. Take the bus from Detroit Bus Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    18h 14m
    $144–230

  3. Train, bus via St. Louis

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    20h 11m
    $372–593

  4. Drive  723.1 mi

    1. Drive from Detroit to Tupelocar car 723.1 mi
    13h 22m
    $132–191

  5. Fly to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Detroit (DTW) to Birmingham–Shuttlesworth International Airport (BHM)plane plane DTW - BHM
    2. Drive from Birmingham-Airport-BHM to Tupelocar car
    6h 14m
    $196–992

  6. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Detroit (DTW) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane DTW - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    6h 13m
    $145–787

  7. Fly to Tupelo Regional Airport

    1. Fly from Detroit (DTW) to Tupelo Regional Airport (TUP)plane plane DTW - TUP
    5h 50m
    $126–670

  8. Fly to Memphis, bus

    1. Fly from Detroit (DTW) to Memphis (MEM)plane plane DTW - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    8h 3m
    $200–1,043

  9. Train, bus

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    18h 39m
    $262–418

  10. Bus via Champaign

    1. Take the bus from Detroit Bus Station to Chicagobus bus
    2. Take the bus from Chicago to Champaign Intermodal Trans Ctrbus bus
    3. Take the bus from Champaign Intermodal Trans Ctr to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    22h 19m
    $166–254

  11. Bus via Atlanta (Greyhound)

    1. Take the bus from Detroit Bus Station to Atlanta Bus Stationbus bus Greyhound US0110 / ...
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    23h 19m
    $175–274

Detroit (DTW) to Golden Triangle Regional Airport (GTR) flights

Calendar40Weekly Planes
Duration6h 33mAverage Duration
Ticket$108Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Detroit to Tupelo.ExpandLaunch map view
  • Distance: 752.3 mi
  • Duration: 7h 12m

What companies run services between Detroit, MI, USA and Tupelo, MS, USA?

You can take a bus from Detroit Bus Station to Tupelo via Nashville Bus Station, Memphis Bus Station, and Tupelo in around 18h 14m. Alternatively, Delta, Corporate Flight Management Inc, and American Airlines fly from Detroit (DTW) to Tupelo Regional Airport (TUP) twice daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

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