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How to get fromBurlington to Mayo Clinicby car, plane, taxi, train, or bus

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There are 8 ways to get from Burlington to Mayo Clinic by car, plane, taxi, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to The Eastern Iowa Airport, fly to Rochester

    best
    1. Drive from Burlington to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Rochester (RST)plane plane CID - RST
    7h 31m
    $64–385

  2. Drive  266.3 mi

    cheapest
    1. Drive from Burlington to Mayo Cliniccar car 266.3 mi
    4h 57m
    $49–71

  3. Taxi, train, bus via Milwaukee

    1. Take the taxi from Burlington to Galesburg Amtrak Stationtaxi taxi
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    13h 11m
    $309–444

  4. Taxi, train, bus

    1. Take the taxi from Burlington to Galesburg Amtrak Stationtaxi taxi
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    14h 58m
    $442–659

  5. Drive to Quad City International Airport, fly to Rochester

    1. Drive from Burlington to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Rochester (RST)plane plane MLI - RST
    7h 13m
    $69–399

  6. Drive to The Eastern Iowa Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Burlington to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Minneapolis–Saint Paul International Airport (MSP)plane plane CID - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 10m
    $118–445

  7. Taxi, train, bus #2

    1. Take the taxi from Burlington to Galesburg Amtrak Stationtaxi taxi
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    13h 40m
    $269–399

  8. Taxi, bus

    1. Take the taxi from Burlington to Galesburgtaxi taxi
    2. Take the bus from Galesburg to Des Moinesbus bus
    3. Take the bus from Des Moines to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Rochesterbus bus
    14h 42m
    $209–294

The Eastern Iowa Airport (CID) to Rochester (RST) flights

Calendar43Weekly Planes
Duration5h 22mAverage Duration
Ticket$48Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Burlington to Mayo Clinic.ExpandLaunch map view
  • Distance: 250.9 mi
  • Duration: 7h 31m

What companies run services between Burlington, IA, USA and Mayo Clinic, MN, USA?

There is no direct connection from Burlington to Mayo Clinic. However, you can drive to Cedar-Rapids-Airport-CID airport, fly to Rochester (RST), walk to Rochester, take the bus to Rochester, then walk to Mayo Clinic. Alternatively, you can take the taxi to Galesburg Amtrak Station, take the train to Chicago Union Station, take the train to Milwaukee, walk to Milwaukee, take the bus to Rochester, then walk to Mayo Clinic.

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