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How to get fromCape Coral to Charlestonby bus, plane, train, or car

Find Transport to Charleston

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There are 6 ways to get from Cape Coral to Charleston by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 30 bus to Ft. Myers, fly

    best
    1. Take the bus from Cc Pwky @ Vincennes St to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    5h 59m
    $106–607

  2. Drive  537.2 mi

    cheapest
    1. Drive from Cape Coral to Charlestoncar car 537.2 mi
    9h 48m
    $98–142

  3. Bus, train (Amtrak)

    1. Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus bus Amtrak Thruway Connecting Service
    2. Take the train from Orlando to Charleston Amtrak Stationtrain train Silver Meteor
    16h 49m

  4. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    8h 27m
    $424–1,140

  5. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    9h 18m
    $518–1,045

  6. Bus, train via Orlando

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the train from Winter Park Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    17h 35m
    $264–420

Cape Coral to Charleston by bus, taxi, and train

Calendar7Weekly Services
Duration17h 35mAverage Duration
Ticket$264Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Coral to Charleston.ExpandLaunch map view
  • Distance: 482 mi
  • Duration: 5h 59m

What companies run services between Cape Coral, FL, USA and Charleston, SC, USA?

There is no direct connection from Cape Coral to Charleston. However, you can take the line 30 bus to South Fort Myers Transfer/P&R, take the line 50 bus to Rsw, walk to Ft. Myers (RSW) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a vehicle from Cape Coral to Transit Mall via Fort Myers Amtrak Bus Stop, Orlando, Orlando, Charleston Amtrak Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 16h 49m.

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