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How to get fromCape Cod to Buffaloby plane, bus (Greyhound), bus, train, car, taxi, or bus (Flixbus)

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There are 8 ways to get from Cape Cod to Buffalo by plane, bus (Greyhound), bus, train, car, taxi, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Buffalo Niagara International Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    7h 3m
    $96–579

  2. Drive  517.1 mi

    cheapest
    1. Drive from Cape Cod to Buffalocar car 517.1 mi
    9h 8m
    $95–137

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h 54m
    $107–165

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 9m
    $301–459

  5. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 45m
    $105–604

  6. Taxi to Provincetown Municipal Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    5h 38m
    $277–1,008

  7. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    8h 16m
    $154–768

  8. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    16h 23m
    $107–165

Cape Cod to Buffalo by bus

Calendar7Weekly Buses
Duration13h 54mAverage Duration
Ticket$107Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Cod to Buffalo.ExpandLaunch map view
  • Distance: 456.7 mi
  • Duration: 7h 3m

What companies run services between Cape Cod, MA, USA and Buffalo, NY, USA?

American Airlines, JetBlue Airways, and two other airlines fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a bus from Town Hall Lawton Bus Shelter to Buffalo via Hyannis Transportation Center, Boston, South Station, and Boston in around 13h 54m.

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